PUBLIC HEALTH ADVISORY CONCERNING FENTANYL AND FENTANYL-LACED SUBSTANCES

NAS Research Projects

In September 2013, the Tennessee Department of Health convened a group of stakeholders to identify key research questions that, if answered, could help to reduce the burden of NAS in Tennessee.  The group identified five key questions:

  • Is it possible to develop a model to predict which mothers are most at risk for delivering a baby with NAS?
  • What is the optimal management of a pregnant woman who is using opioid medications in order to minimize risk to the baby and minimize risk of the baby developing NAS?
  • What is the optimal management of an infant with NAS?
  • What are key strategies for changing provider knowledge and behavior?
  • How can contraceptive use be increased among opioid-using women?

 In December 2013, the Department released a request for applications to solicit research proposals related to these questions.  Proposals were selected through a competitive process and five Tennessee teams were awarded small grants to address the research questions.  A study summary and final report for each project are provided below.


Key Question Research Team and Project Title Study Summary Final Project Report

Is it possible to develop a model to predict which mothers are most at risk for delivering a baby with NAS?

Vanderbilt University Medical Center

"Prescription Opioid Prescribing Patterns as Predictors of Neonatal Abstinence Syndrome"

What is the optimal management of a pregnant woman who is using opioid medications in order to minimize risk to the baby and minimize risk of the baby developing NAS?

Cherokee Health Systems
High Risk Obstetrical Consultants Group

"Management of Opiate Addicted Pregnant Women to Decrease Incidence of Neonatal Abstinence Syndrome"

What is the optimal management of an infant with NAS?

Vanderbilt University School of Nursing
East Tennessee Children's Hospital

"Neonatal Abstinence Syndrome Management Trends in Tennessee"

What are key strategies for changing provider knowledge and behavior?

East Tennessee State University
Appalachian Research Network

"Improving Tennessee Health Care Providers Understanding of Neonatal Abstinence Syndrome"


How can contraceptive use be increased among opioid-using women?

Knox County Health Department
University of Tennessee Department of Public Health

"Risk and Facilitating Factors of Contraception Use Among Female Methadone Clinic Patients, Ages 18-45"